A tiny frame was a piece of evidence in Apollo Justice and Phoenix Wright's investigation into the murder of Drew Misham.
Drew's daughter Vera used it to frame a commemorative stamp of Troupe Gramarye that Kristoph Gavin had sent to the Drew Studio. She believed that Gavin had gifted it to her as a Troupe Gramarye memento. Later, Phoenix Wright visited Drew Studio and met Vera there. After learning about her problem with people and the outside world, he saw the stamp and learned that she was a huge fan of Troupe Gramarye. He used this information to coax her into talking with him.
Seven years later, Drew wrote a letter to Gavin and used the commemorative stamp, not having any other stamp to use. However, it turned out that the stamp had been poisoned with atroquinine, and he died. During Justice's investigation into the murder, he met Ema Skye at Drew Studio, and they sprayed the frame with a chemical that could detect atroquinine residue, finding traces of the poison there.